CD2H Labs

Welcome to CD2H Labs

Welcome to CD2H Labs

We welcome and encourage CTSA members to engage with our CD2H project prototypes here and provide feedback and suggestions for further iteration and implementation.

Explore Current Lab Prototypes

Explore current projects, test prototypes and submit your feedback below. We encourage you to reach out directly to project leads to learn more and get involved.

Data

Software

CTSAsearch
Project Lead: David Eichmann
CD2H project

CTSAsearch is a integrated discovery engine using VIVO ontology compliant Linked Open Data published by 87 institutions using a number of open source and commercial research profiling systems. CTSAsearch is an integrated discovery engine using Linked Open Data published by members of the CTSA Consortium and other interested parties using a number of different tools (VIVO, Harvard Profiles, Elsevier Pure, …). Results are available in both text and graphical forms, along with multiple analytic visualizations. Services are also available for Consortium members to embed data into their local sites.

Acknowledgements: Grants: 3UL1TR000128-10S1 and U24TR002306
LOINC2HPO
Project Lead: Peter Robinson Peter.Robinson@jax.org
Semantically linking laboratory observations in EHRs to medical phenotypes

LOINC is a standard for encoding laboratory observations that is widely used by labs, healthcare organizations, etc. The Human Phenotype Ontology (HPO) is widely used in the rare-disease community as a standard for reporting and analyzing phenotypic abnormalities. This project is creating a computable semantic bridge between both resources that will allow LOINC-encoded laboratory data in EHRs to be transformed in the corresponding HPO codes.

Acknowledgements: LOINC (Regenstrief Institute), NCATS
Data Discovery Engine
Project Lead: Chunlei Wu person@email.com
Reusable Datasets through Data Discovery

This data Workgroup project is targeted to bridge the community-developed metadata standards and the CTSA translational and clinical datasets with a set of metadata authoring tools, allowing better data discovery across CTSA hubs and facilitating the new collaboration between sites. Data-sharing is becoming a more and more common practice among today’s research community. Do you have a dataset/study ready to share across the CTSA Program or the entire research community? CD2H is here to help you promote your dataset/study and work together with you to standardize the dataset metadata to enhance visibility. Nominate your dataset here and your dataset will be considered to be highlighted in our coming CD2H newsletter. CD2H’s Data Workgroup will also contact you to offer help on the metadata-authoring.

Acknowledgements: Scripps Research Institute, Northwestern University, and everyone participated in the breakout session at the recent CD2H All hands meeting for their contributions of ideas and comments.
Leaf Cloud Pilot
Project Lead: Kari Stephens kstephen@uw.edu

The demonstration project will provide opportunities for CD2H to discover a pathway to: 1) data sharing governance structures that could be a model for the CTSA Program, 2) cloud infrastructure that could be adapted for use by multiple CTSAs, operating multiple data models, and 3) cloud vendor partnerships. It will scale an existing front end tool for self-service against an OMOP repository that can be co-opted by other CTSA institutes in the near term. This project will create groundwork for building scalable solutions that allow more nimble data sharing within and across CTSAs (i.e., API solutions for multiple self-service tools to operate against multiple shared data models like OMOP, i2b2, and FHIR).

Acknowledgements: University of Washington, Washington University in St. Louis
CIELO
Project Lead: Philip Payne prpayne@wustl.edu
CD2H project
An open science environment for health analytics

CIELO is an integrated environment that allows teams of researchers and technologists to develop, discover, and adopt or adapt software, tools, and algorithms, along with corresponding data sets, that collectively can support the conduct of clinical and translational research.

Acknowledgements: Washington University in St. Louis, AcademyHealth

Phase 2 projects will be announced in early January. See what projects we are considering here. Please feel free to reach out if you are interested in collaborating on this work. Project lead contact information is listed.

Get Involved With a CD2H Workgroup
Get Involved With a CD2H Workgroup
CD2H Community Workgroups are currently focused on three key areas: Data; Software, Tools and Algorithms; and People, Expertise and Attribution. We encourage broad participation by welcoming diverse perspectives and academic disciplines from those interested in participating in Workgroups. Explore opportunities to get involved below.
See What Projects are underway