The National COVID Cohort Collaborative (N3C): covid.cd2h.org

By leveraging our collective data resources, unparalleled analytics expertise, and medical insights from expert clinicians, we can synergize discoveries that address this pandemic beyond the sum of our parts. The National COVID Cohort Collaborative (N3C) is a platform for the Clinical and Translational Science Award (CTSA) hubs, distributed clinical data networks (PCORnet, OHDSI, ACT, TriNetX), and other partner organizations interested in joining. The N3C aims to improve the efficiency and accessibility of analyses with COVID-19 clinical data, expand our ability to analyze and understand COVID, and demonstrate a novel approach for collaborative pandemic data sharing.

The N3C will accept data via multiple data models and transform them into a common analytic model. The cloud-based collaborative portal will enable development of machine learning and other informatics tools that require a large row-level dataset, and will be overseen by a data access committee. This global pandemic presents a unique opportunity to bring together top informatics experts from around the country to address our collective challenges.

The N3C resource will offer a valuable and complementary contribution, not only for aiding the COVID-19 crisis, but for transforming how we perform global research as a nation. We believe this portal will provide additional assets needed to rapidly develop the analytics that clinical centers and physicians need now. 

To learn more, please visit covid.cd2h.org.


CD2H Community Cores:

Specific Aims

Join us in our mission to advance informatics innovation across the translational science spectrum and improve patient care. 



CD2H Phase III & IV

CD2H is pleased to announce Phase III & IV projects. Over 20 proposals, including ongoing infrastructure projects, were independently reviewed by a panel of community leaders, hub PIs, and the CD2H Steering Committee. Nine projects best fit the Phase III strategy, and will be facilitated within their respective CD2H cores under the direction of the core leaders, community co-chairs, and project leads. CD2H gratefully thanks everyone who submitted proposals and assisted in the review process.

Throughout the phases of the grant award, CD2H aims to enhance alignment with community needs, provide a balance of projects across CD2H community cores, and streamline the number of projects to ensure adequate resource allocation for project management and engagement. Projects that were not chosen for Phase III will be supported in their maturation and coordination by community cores and/or within the context of the Informatics Enterprise Committee (iEC).

CD2H carries on the mission to change the culture of how data is shared across the Translational Research Community and strives to expand outreach for education, training, and leadership. CD2H thanks everyone for their dedicated work in the advancement of translational science.


The CTSA National Center for Data to Health (CD2H) accelerates advancements in informatics by utilizing findable, accessible, interoperable, and resusable (FAIR) principles to promote collaboration across the Clinical and Translational Science Awards (CTSA) Program community.

CD2H provides support and infrastructure to ensure a smooth and successful transition for CTSAs. Our tools and resources make it simple and valuable for CTSA Program members to get engaged, connect with peers and contribute. By increasing collaboration, the CD2H fosters a robust translational science informatics ecosystem that collectively develops solutions to solve clinical problems faster, more efficiently, and more effectively.